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Of Rings and Rods: Regulating Cohesin Entrapment of DNA to Generate Intra- and Intermolecular Tethers

The clinical relevance of cohesin in DNA repair, tumorigenesis, and severe birth defects continues to fuel efforts in understanding cohesin structure, regulation, and enzymology. Early models depicting huge cohesin rings that entrap two DNA segments within a single lumen are fading into obscurity ba...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Autor principal: Skibbens, Robert V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082857/
https://ncbi.nlm.nih.gov/pubmed/27788133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006337
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