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Transcriptional targeting of replication-defective adenovirus transgene expression to smooth muscle cells in vivo.

Gene transfer using replication-defective adenoviruses (RDAd) holds promise for the treatment of vascular proliferative disorders, but is potentially limited by the capacity of these viruses to infect multiple cell lineages. We have generated an RDAd vector, designated AdSM22-lacZ, which encodes the...

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Detalles Bibliográficos
Main Authors: Kim, S, Lin, H, Barr, E, Chu, L, Leiden, J M, Parmacek, M S
Formato: Artigo
Idioma:Inglês
Publicado: 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC508275/
https://ncbi.nlm.nih.gov/pubmed/9276717
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