Adenovirus-Mediated Expression of a Ribozyme to c-myb mRNA Inhibits Smooth Muscle Cell Proliferation and Neointima Formation In Vivo

Smooth muscle cell (SMC) proliferation is an important component of restenosis in response to injury after balloon angioplasty. Inhibition of proliferation in vivo can limit neointima hyperplasia in animal models of restenosis. Ribozymes against c-myb mRNA have been shown to be effective inhibitors...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Macejak, Dennis G., Lin, Hua, Webb, Saiphone, Chase, Jennifer, Jensen, Kristi, Jarvis, Thale C., Leiden, Jeffrey M., Couture, Larry
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Gene Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC104301/
https://ncbi.nlm.nih.gov/pubmed/10438864
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky