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Inhibition of vascular smooth muscle cell proliferation by ribozymes that cleave c-myb mRNA.

Proliferation of injured smooth muscle cells contributes to the reocclusion or restenosis of coronary arteries that often occurs following angioplasty procedures. We have identified and optimized nuclease-resistant ribozymes that efficiently cleave c-myb RNA. Three ribozymes targeting different site...

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Autori principali: Jarvis, T C, Alby, L J, Beaudry, A A, Wincott, F E, Beigelman, L, McSwiggen, J A, Usman, N, Stinchcomb, D T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369383/
https://ncbi.nlm.nih.gov/pubmed/8665409
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