NK-CD11c+ Cell Crosstalk in Diabetes Enhances IL-6-Mediated Inflammation during Mycobacterium tuberculosis Infection

In this study, we developed a mouse model of type 2 diabetes mellitus (T2DM) using streptozotocin and nicotinamide and identified factors that increase susceptibility of T2DM mice to infection by Mycobacterium tuberculosis (Mtb). All Mtb-infected T2DM mice and 40% of uninfected T2DM mice died within...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Cheekatla, Satyanarayana Swamy, Tripathi, Deepak, Venkatasubramanian, Sambasivan, Nathella, Pavan Kumar, Paidipally, Padmaja, Ishibashi, Munenori, Welch, Elwyn, Tvinnereim, Amy R., Ikebe, Mitsuo, Valluri, Vijaya Lakshmi, Babu, Subash, Kornfeld, Hardy, Vankayalapati, Ramakrishna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082658/
https://ncbi.nlm.nih.gov/pubmed/27783671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005972
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