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Subendothelial retention of lipoprotein (a). Evidence that reduced heparan sulfate promotes lipoprotein binding to subendothelial matrix.

Vessel wall subendothelial extracellular matrix, a dense mesh formed of collagens, fibronectin, laminin, and proteoglycans, has important roles in lipid and lipoprotein retention and cell adhesion. In atherosclerosis, vessel wall heparan sulfate proteoglycans (HSPG) are decreased and we therefore te...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Pillarisetti, S, Paka, L, Obunike, J C, Berglund, L, Goldberg, I J
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508259/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9259586/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119602
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