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Subendothelial retention of lipoprotein (a). Evidence that reduced heparan sulfate promotes lipoprotein binding to subendothelial matrix.

Vessel wall subendothelial extracellular matrix, a dense mesh formed of collagens, fibronectin, laminin, and proteoglycans, has important roles in lipid and lipoprotein retention and cell adhesion. In atherosclerosis, vessel wall heparan sulfate proteoglycans (HSPG) are decreased and we therefore te...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Pillarisetti, S, Paka, L, Obunike, J C, Berglund, L, Goldberg, I J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508259/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9259586/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119602
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