Subendothelial retention of lipoprotein (a). Evidence that reduced heparan sulfate promotes lipoprotein binding to subendothelial matrix.

Vessel wall subendothelial extracellular matrix, a dense mesh formed of collagens, fibronectin, laminin, and proteoglycans, has important roles in lipid and lipoprotein retention and cell adhesion. In atherosclerosis, vessel wall heparan sulfate proteoglycans (HSPG) are decreased and we therefore te...

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Pubblicato in:	J Clin Invest
Autori principali:	Pillarisetti, S, Paka, L, Obunike, J C, Berglund, L, Goldberg, I J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508259/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9259586/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119602
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