HCV core protein inhibits polarization and activity of both M1 and M2 macrophages through the TLR2 signaling pathway

Hepatitis C virus (HCV) establishes persistent infection in most infected patients, and eventually causes chronic hepatitis, cirrhosis, and hepatocellular carcinoma in some patients. Monocytes and macrophages provide the first line of defense against pathogens, but their roles in HCV infection remai...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Qianqian, Wang, Yang, Zhai, Naicui, Song, Hongxiao, Li, Haijun, Yang, Yang, Li, Tianyang, Guo, Xiaolin, Chi, Baorong, Niu, Junqi, Crispe, Ian Nicholas, Su, Lishan, Tu, Zhengkun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082373/
https://ncbi.nlm.nih.gov/pubmed/27786268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36160
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