Hepatitis C Virus Induces MDSCs-Like Monocytes through TLR2/PI3K/AKT/STAT3 Signaling

BACKGROUND AND AIMS: Recent studies reveal the accumulation of myeloid derived suppressor cells (MDSCs) in human peripheral blood mononuclear cells (PBMCs) following HCV infection, which may facilitate and maintain HCV persistent infection. The mechanisms by which HCV induces MDSCs are poorly unders...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhai, Naicui, Li, Haijun, Song, Hongxiao, Yang, Yang, Cui, An, Li, Tianyang, Niu, Junqi, Crispe, Ian Nicholas, Su, Lishan, Tu, Zhengkun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256909/
https://ncbi.nlm.nih.gov/pubmed/28114346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170516
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