Hepatitis C Virus Induces MDSCs-Like Monocytes through TLR2/PI3K/AKT/STAT3 Signaling.

Recent studies reveal the accumulation of myeloid derived suppressor cells (MDSCs) in human peripheral blood mononuclear cells (PBMCs) following HCV infection, which may facilitate and maintain HCV persistent infection. The mechanisms by which HCV induces MDSCs are poorly understood. In the present...

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Main Authors: Naicui Zhai, Haijun Li, Hongxiao Song, Yang Yang, An Cui, Tianyang Li, Junqi Niu, Ian Nicholas Crispe, Lishan Su, Zhengkun Tu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2017-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC5256909?pdf=render
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