Resveratrol Administration Increases Transthyretin Protein Levels, Ameliorating AD Features: The Importance of Transthyretin Tetrameric Stability

Previous in vivo work showed that resveratrol has beneficial effects in Alzheimer’s disease (AD) pathology, resulting in increased expression of transthyretin (TTR). TTR binds amyloid-beta (Aβ) peptide, avoiding its aggregation and toxicity, and is reduced in the cerebrospinal fluid (CSF) and plasma...

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Vydáno v:Mol Med
Hlavní autoři: Santos, Luís Miguel, Rodrigues, Daniela, Alemi, Mobina, Silva, Sara Costa, Ribeiro, Carlos Alexandre, Cardoso, Isabel
Médium: Artigo
Jazyk:Inglês
Vydáno: Feinstein Institute for Medical Research 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082299/
https://ncbi.nlm.nih.gov/pubmed/27385446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00124
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