Resveratrol Administration Increases Transthyretin Protein Levels, Ameliorating AD Features: The Importance of Transthyretin Tetrameric Stability

Previous in vivo work showed that resveratrol has beneficial effects in Alzheimer’s disease (AD) pathology, resulting in increased expression of transthyretin (TTR). TTR binds amyloid-beta (Aβ) peptide, avoiding its aggregation and toxicity, and is reduced in the cerebrospinal fluid (CSF) and plasma...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Santos, Luís Miguel, Rodrigues, Daniela, Alemi, Mobina, Silva, Sara Costa, Ribeiro, Carlos Alexandre, Cardoso, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Feinstein Institute for Medical Research 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082299/
https://ncbi.nlm.nih.gov/pubmed/27385446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00124
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