Emetine Di-HCl Attenuates Type 1 Diabetes Mellitus in Mice

Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by β cell destruction, insulin deficiency and hyperglycemia. Activated macrophages and autoimmune T cells play a crucial role in the pathogenesis of hyperglycemia in NOD murine diabetes models, but the molecular mechanisms...

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發表在:Mol Med
Main Authors: Hudson, LaQueta K, Dancho, Meghan E, Li, Jianhua, Bruchfeld, Johanna B, Ragab, Ahmed A, He, Mingzhu M, Bragg, Meaghan, Lenaghan, Delaney, Quinn, Michael D, Fritz, Jason R, Tanzi, Matthew V, Silverman, Harold A, Hanes, William M, Levine, Yaakov A, Pavlov, Valentin A, Olofsson, Peder S, Roth, Jesse, Al-Abed, Yousef, Andersson, Ulf, Tracey, Kevin J, Chavan, Sangeeta S
格式: Artigo
語言:Inglês
出版: Feinstein Institute for Medical Research 2016
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082289/
https://ncbi.nlm.nih.gov/pubmed/27341452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00082
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