Emetine Di-HCl Attenuates Type 1 Diabetes Mellitus in Mice

Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by β cell destruction, insulin deficiency and hyperglycemia. Activated macrophages and autoimmune T cells play a crucial role in the pathogenesis of hyperglycemia in NOD murine diabetes models, but the molecular mechanisms...

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Foilsithe in:Mol Med
Main Authors: Hudson, LaQueta K, Dancho, Meghan E, Li, Jianhua, Bruchfeld, Johanna B, Ragab, Ahmed A, He, Mingzhu M, Bragg, Meaghan, Lenaghan, Delaney, Quinn, Michael D, Fritz, Jason R, Tanzi, Matthew V, Silverman, Harold A, Hanes, William M, Levine, Yaakov A, Pavlov, Valentin A, Olofsson, Peder S, Roth, Jesse, Al-Abed, Yousef, Andersson, Ulf, Tracey, Kevin J, Chavan, Sangeeta S
Formáid: Artigo
Teanga:Inglês
Foilsithe: Feinstein Institute for Medical Research 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082289/
https://ncbi.nlm.nih.gov/pubmed/27341452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00082
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