Xanomeline suppresses excessive pro-inflammatory cytokine responses through neural signal-mediated pathways and improves survival in lethal inflammation

Inflammatory conditions characterized by excessive immune cell activation and cytokine release, are associated with bidirectional immune system-brain communication, underlying sickness behavior and other physiological responses. The vagus nerve has an important role in this communication by conveyin...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Rosas-Ballina, Mauricio, Ferrer, Sergio Valdés, Dancho, Meghan, Ochani, Mahendar, Katz, David, Cheng, Kai Fan, Olofsson, Peder S., Chavan, Sangeeta S., Al-Abed, Yousef, Tracey, Kevin J., Pavlov, Valentin A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624331/
https://ncbi.nlm.nih.gov/pubmed/25063706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2014.07.010
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