HIGH-MOBILITY GROUP BOX 1 MEDIATES PERSISTENT SPLENOCYTE PRIMING IN SEPSIS SURVIVORS: EVIDENCE FROM A MURINE MODEL

Severe sepsis is a life-threatening complication of infection and injury affecting more than 700,000 people in the United States each year. Two thirds of patients with severe sepsis will survive to be discharged. Survivors have high incidence of cognitive impairment, immune dysregulation, functional...

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Udgivet i:Shock
Main Authors: Valdés-Ferrer, Sergio I., Rosas-Ballina, Mauricio, Olofsson, Peder S., Lu, Ben, Dancho, Meghan E., Li, JianHua, Yang, Huan, Pavlov, Valentin A., Chavan, Sangeeta S., Tracey, Kevin J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582752/
https://ncbi.nlm.nih.gov/pubmed/24089009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000050
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