Emetine Di-HCl Attenuates Type 1 Diabetes Mellitus in Mice

Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by β cell destruction, insulin deficiency and hyperglycemia. Activated macrophages and autoimmune T cells play a crucial role in the pathogenesis of hyperglycemia in NOD murine diabetes models, but the molecular mechanisms...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Hudson, LaQueta K, Dancho, Meghan E, Li, Jianhua, Bruchfeld, Johanna B, Ragab, Ahmed A, He, Mingzhu M, Bragg, Meaghan, Lenaghan, Delaney, Quinn, Michael D, Fritz, Jason R, Tanzi, Matthew V, Silverman, Harold A, Hanes, William M, Levine, Yaakov A, Pavlov, Valentin A, Olofsson, Peder S, Roth, Jesse, Al-Abed, Yousef, Andersson, Ulf, Tracey, Kevin J, Chavan, Sangeeta S
Formato: Artigo
Idioma:Inglês
Publicado em: Feinstein Institute for Medical Research 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082289/
https://ncbi.nlm.nih.gov/pubmed/27341452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00082
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