Emetine Di-HCl Attenuates Type 1 Diabetes Mellitus in Mice

Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by β cell destruction, insulin deficiency and hyperglycemia. Activated macrophages and autoimmune T cells play a crucial role in the pathogenesis of hyperglycemia in NOD murine diabetes models, but the molecular mechanisms...

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Publicado en:Mol Med
Autores principales: Hudson, LaQueta K, Dancho, Meghan E, Li, Jianhua, Bruchfeld, Johanna B, Ragab, Ahmed A, He, Mingzhu M, Bragg, Meaghan, Lenaghan, Delaney, Quinn, Michael D, Fritz, Jason R, Tanzi, Matthew V, Silverman, Harold A, Hanes, William M, Levine, Yaakov A, Pavlov, Valentin A, Olofsson, Peder S, Roth, Jesse, Al-Abed, Yousef, Andersson, Ulf, Tracey, Kevin J, Chavan, Sangeeta S
Formato: Artigo
Lenguaje:Inglês
Publicado: Feinstein Institute for Medical Research 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082289/
https://ncbi.nlm.nih.gov/pubmed/27341452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00082
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