Generation of an in vitro 3D PDAC stroma rich spheroid model

Pancreatic ductal adenocarcinoma (PDAC) is characterized by a prominent desmoplastic/stromal reaction, which contributes to the poor clinical outcome of this disease. Therefore, greater understanding of the stroma development and tumor-stroma interactions is highly required. Pancreatic stellate cell...

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Pubblicato in:Biomaterials
Autori principali: Ware, Matthew J., Keshishian, Vazrik, Law, Justin J., Ho, Jason C, Favela, Carlos A, Rees, Paul, Smith, Billie, Mohammad, Sayeeduddin, Hwang, Rosa F., Rajapakshe, Kimal, Coarfa, Cristian, Huang, Shixia, Edwards, Dean P., Corr, Stuart J., Godin, Biana, Curley, Steven A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082237/
https://ncbi.nlm.nih.gov/pubmed/27627810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.08.041
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