Massively Parallel Delivery of Large-Sized Cargo into Mammalian Cells with Light Pulses

We report a high-throughput platform for delivering large cargo into 100,000 cells in 1 min. An array of micro-cavitation bubbles explode in response to laser pulsing, forming pores in adjacent cell membranes, and immediately thereafter, pressurized flows drive slow diffusing cargo through these por...

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Bibliographic Details
Published in:Nat Methods
Main Authors: Wu, Yi-Chien, Wu, Ting-Hsiang, Clemens, Daniel L., Lee, Bai-Yu, Wen, Ximiao, Horwitz, Marcus A., Teitell, Michael A., Chiou, Pei-Yu
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082232/
https://ncbi.nlm.nih.gov/pubmed/25849636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3357
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