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Massively Parallel Delivery of Large-Sized Cargo into Mammalian Cells with Light Pulses

We report a high-throughput platform for delivering large cargo into 100,000 cells in 1 min. An array of micro-cavitation bubbles explode in response to laser pulsing, forming pores in adjacent cell membranes, and immediately thereafter, pressurized flows drive slow diffusing cargo through these por...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Methods
Prif Awduron: Wu, Yi-Chien, Wu, Ting-Hsiang, Clemens, Daniel L., Lee, Bai-Yu, Wen, Ximiao, Horwitz, Marcus A., Teitell, Michael A., Chiou, Pei-Yu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082232/
https://ncbi.nlm.nih.gov/pubmed/25849636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3357
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