Oncostatin M is a proinflammatory mediator. In vivo effects correlate with endothelial cell expression of inflammatory cytokines and adhesion molecules.

Oncostatin M is a member of the IL-6 family of cytokines that is primarily known for its effects on cell growth. Endothelial cells have an abundance of receptors for oncostatin M, and may be its primary target. We determined if oncostatin M induces a key endothelial cell function, initiation of the...

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Bibliographic Details
Main Authors: Modur, V, Feldhaus, M J, Weyrich, A S, Jicha, D L, Prescott, S M, Zimmerman, G A, McIntyre, T M
Format: Artigo
Language:Inglês
Published: 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC508176/
https://ncbi.nlm.nih.gov/pubmed/9202068
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