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Sirtuin 1 Promotes Deacetylation of Oct4 and Maintenance of Naïve Pluripotency
The enhancer landscape is dramatically restructured as naïve preimplantation epiblasts transition to the post-implantation state of primed pluripotency. A key factor in this process is Otx2, which is upregulated during the early stages of this transition and ultimately recruits Oct4 to a different s...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5081691/ https://ncbi.nlm.nih.gov/pubmed/27732856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.046 |
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