Distinct Enhancer Activity of Oct4 in Naive and Primed Mouse Pluripotency

Naive and primed pluripotent stem cells (PSCs) and germ cells express the Oct4 gene. The Oct4 gene contains two cis-regulatory elements, the distal enhancer (DE) and proximal enhancer (PE), which differentially control Oct4 expression in a cell-type-specific and stage-specific manner. Here, we gener...

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Bibliografiset tiedot
Julkaisussa:Stem Cell Reports
Päätekijät: Choi, Hyun Woo, Joo, Jin Young, Hong, Yean Ju, Kim, Jong Soo, Song, Hyuk, Lee, Jeong Woong, Wu, Guangming, Schöler, Hans R., Do, Jeong Tae
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106531/
https://ncbi.nlm.nih.gov/pubmed/28157483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.09.012
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