Distinct Enhancer Activity of Oct4 in Naive and Primed Mouse Pluripotency

Naive and primed pluripotent stem cells (PSCs) and germ cells express the Oct4 gene. The Oct4 gene contains two cis-regulatory elements, the distal enhancer (DE) and proximal enhancer (PE), which differentially control Oct4 expression in a cell-type-specific and stage-specific manner. Here, we gener...

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Publicado no:Stem Cell Reports
Main Authors: Choi, Hyun Woo, Joo, Jin Young, Hong, Yean Ju, Kim, Jong Soo, Song, Hyuk, Lee, Jeong Woong, Wu, Guangming, Schöler, Hans R., Do, Jeong Tae
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106531/
https://ncbi.nlm.nih.gov/pubmed/28157483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.09.012
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