Transcriptional Activation by Oct4 Is Sufficient for the Maintenance and Induction of Pluripotency

Oct4 is an essential regulator of pluripotency in vivo and in vitro in embryonic stem cells, as well as a key mediator of the reprogramming of somatic cells into induced pluripotent stem cells. It is not known whether activation and/or repression of specific genes by Oct4 is relevant to these functi...

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Bibliografiset tiedot
Päätekijät: Hammachi, Fella, Morrison, Gillian M., Sharov, Alexei A., Livigni, Alessandra, Narayan, Santosh, Papapetrou, Eirini P., O'Malley, James, Kaji, Keisuke, Ko, Minoru S.H., Ptashne, Mark, Brickman, Joshua M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2012
Aiheet:
Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778438/
https://ncbi.nlm.nih.gov/pubmed/22832160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2011.12.002
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