Bone loss and aggravated autoimmune arthritis in HLA-DRβ1-bearing humanized mice following oral challenge with Porphyromonas gingivalis

BACKGROUND: The linkage between periodontal disease and rheumatoid arthritis is well established. Commonalities among the two are that both are chronic inflammatory diseases characterized by bone loss, an association with the shared epitope susceptibility allele, and anti-citrullinated protein antib...

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Publicado en:Arthritis Res Ther
Autores principales: Sandal, Indra, Karydis, Anastasios, Luo, Jiwen, Prislovsky, Amanda, Whittington, Karen B., Rosloniec, Edward F., Dong, Chen, Novack, Deborah V., Mydel, Piotr, Zheng, Song Guo, Radic, Marko Z., Brand, David D.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081677/
https://ncbi.nlm.nih.gov/pubmed/27784339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1143-6
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