Bone loss and aggravated autoimmune arthritis in HLA-DRβ1-bearing humanized mice following oral challenge with Porphyromonas gingivalis

BACKGROUND: The linkage between periodontal disease and rheumatoid arthritis is well established. Commonalities among the two are that both are chronic inflammatory diseases characterized by bone loss, an association with the shared epitope susceptibility allele, and anti-citrullinated protein antib...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Sandal, Indra, Karydis, Anastasios, Luo, Jiwen, Prislovsky, Amanda, Whittington, Karen B., Rosloniec, Edward F., Dong, Chen, Novack, Deborah V., Mydel, Piotr, Zheng, Song Guo, Radic, Marko Z., Brand, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081677/
https://ncbi.nlm.nih.gov/pubmed/27784339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1143-6
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