Genomic charting of ribosomally synthesized natural product chemical space facilitates targeted mining

Microbial natural products are an evolved resource of bioactive small molecules, which form the foundation of many modern therapeutic regimes. Ribosomally synthesized and posttranslationally modified peptides (RiPPs) represent a class of natural products which have attracted extensive interest for t...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Skinnider, Michael A., Johnston, Chad W., Edgar, Robyn E., Dejong, Chris A., Merwin, Nishanth J., Rees, Philip N., Magarvey, Nathan A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081660/
https://ncbi.nlm.nih.gov/pubmed/27698135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609014113
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