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Genomic charting of ribosomally synthesized natural product chemical space facilitates targeted mining

Microbial natural products are an evolved resource of bioactive small molecules, which form the foundation of many modern therapeutic regimes. Ribosomally synthesized and posttranslationally modified peptides (RiPPs) represent a class of natural products which have attracted extensive interest for t...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Skinnider, Michael A., Johnston, Chad W., Edgar, Robyn E., Dejong, Chris A., Merwin, Nishanth J., Rees, Philip N., Magarvey, Nathan A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081660/
https://ncbi.nlm.nih.gov/pubmed/27698135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609014113
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