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Hi-C-constrained physical models of human chromosomes recover functionally-related properties of genome organization
Combining genome-wide structural models with phenomenological data is at the forefront of efforts to understand the organizational principles regulating the human genome. Here, we use chromosome-chromosome contact data as knowledge-based constraints for large-scale three-dimensional models of the hu...
Gardado en:
| Publicado en: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5081523/ https://ncbi.nlm.nih.gov/pubmed/27786255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35985 |
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