Handling realistic assumptions in hypothesis testing of 3D co-localization of genomic elements

The study of chromatin 3D structure has recently gained much focus owing to novel techniques for detecting genome-wide chromatin contacts using next-generation sequencing. A deeper understanding of the architecture of the DNA inside the nucleus is crucial for gaining insight into fundamental process...

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Main Authors: Paulsen, Jonas, Lien, Tonje G., Sandve, Geir Kjetil, Holden, Lars, Borgan, Ørnulf, Glad, Ingrid K., Hovig, Eivind
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Computational Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664813/
https://ncbi.nlm.nih.gov/pubmed/23571755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt227
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