Scrapie-associated prion protein accumulates in astrocytes during scrapie infection.
In the course of scrapie, a transmissible spongiform encephalopathy caused by an unconventional agent, a normal cellular protein is converted to an abnormal form that copurifies with infectivity and aggregates to form deposits of amyloid. We have used immunocytochemistry and methods that enhance det...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1991
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50813/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1671170/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.2.375 |
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