Scrapie-associated prion protein accumulates in astrocytes during scrapie infection.

In the course of scrapie, a transmissible spongiform encephalopathy caused by an unconventional agent, a normal cellular protein is converted to an abnormal form that copurifies with infectivity and aggregates to form deposits of amyloid. We have used immunocytochemistry and methods that enhance det...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Diedrich, J F, Bendheim, P E, Kim, Y S, Carp, R I, Haase, A T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50813/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1671170/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.2.375
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