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Fatty acid analogue N-arachidonoyl taurine restores function of I(Ks) channels with diverse long QT mutations
About 300 loss-of-function mutations in the I(Ks) channel have been identified in patients with Long QT syndrome and cardiac arrhythmia. How specific mutations cause arrhythmia is largely unknown and there are no approved I(Ks) channel activators for treatment of these arrhythmias. We find that seve...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5081249/ https://ncbi.nlm.nih.gov/pubmed/27690226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20272 |
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