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Revisiting antibody modeling assessment for CDR-H3 loop
The antigen-binding site of antibodies, also known as complementarity-determining region (CDR), has hypervariable sequence properties. In particular, the third CDR loop of the heavy chain, CDR-H3, has such variability in its sequence, length, and conformation that ordinary modeling techniques cannot...
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| Vydáno v: | Protein Eng Des Sel |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5081041/ https://ncbi.nlm.nih.gov/pubmed/27515703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzw028 |
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