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The diversity of H3 loops determines the antigen‐binding tendencies of antibody CDR loops
Of the complementarity‐determining regions (CDRs) of antibodies, H3 loops, with varying amino acid sequences and loop lengths, adopt particularly diverse loop conformations. The diversity of H3 conformations produces an array of antigen recognition patterns involving all the CDRs, in which the resid...
Gardado en:
| Publicado en: | Protein Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4941225/ https://ncbi.nlm.nih.gov/pubmed/26749247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2874 |
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