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The diversity of H3 loops determines the antigen‐binding tendencies of antibody CDR loops
Of the complementarity‐determining regions (CDRs) of antibodies, H3 loops, with varying amino acid sequences and loop lengths, adopt particularly diverse loop conformations. The diversity of H3 conformations produces an array of antigen recognition patterns involving all the CDRs, in which the resid...
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Publicado no: | Protein Sci |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4941225/ https://ncbi.nlm.nih.gov/pubmed/26749247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2874 |
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