Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors.
We have investigated the metabolic actions of recombinant human IGF-1 in mice genetically deficient of insulin receptors (IR-/-). After intraperitoneal administration, IGF-1 caused a prompt and sustained decrease of plasma glucose levels in IR-/- mice. Plasma free fatty acid concentrations were unaf...
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| Publicado no: | J Clin Invest |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508095/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9153298/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119438 |
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