YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites.

Tyrosine phosphorylation of insulin receptor substrate 1 (IRS-1) by the activated receptors for insulin, IGF-1, and various cytokines creates binding sites for signaling proteins with Src homology 2 domains (SH2 proteins). Determining the role of specific SH2 proteins during insulin signaling has be...

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Detalhes bibliográficos
Main Authors: Myers, M G, Zhang, Y, Aldaz, G A, Grammer, T, Glasheen, E M, Yenush, L, Wang, L M, Sun, X J, Blenis, J, Pierce, J H, White, M F
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231411/
https://ncbi.nlm.nih.gov/pubmed/8754813
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