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β-Arrestin 1’s Interaction with TC45 Attenuates Stat signaling by dephosphorylating Stat to inhibit antimicrobial peptide expression

Impaired phosphatase activity leads to the persistent activation of signal transducers and activators of transcription (Stat). In mammals, Stat family members are often phosphorylated or dephosphorylated by the same enzymes. To date, only one Stat similar to mammalian Stat5a/b has been found in crus...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sun, Jie-Jie, Yang, Hui-Ting, Niu, Guo-Juan, Feng, Xiao-Wu, Lan, Jiang-Feng, Zhao, Xiao-Fan, Wang, Jin-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080627/
https://ncbi.nlm.nih.gov/pubmed/27782165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35808
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