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Valproate inhibits MAP kinase signalling and cell cycle progression in S. cerevisiae
The mechanism of action of valproate (VPA), a widely prescribed short chain fatty acid with anticonvulsant and anticancer properties, remains poorly understood. Here, the yeast Saccharomyces cerevisiae was used as model to investigate the biological consequences of VPA exposure. We found that low pH...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5080547/ https://ncbi.nlm.nih.gov/pubmed/27782169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36013 |
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