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Valproate inhibits MAP kinase signalling and cell cycle progression in S. cerevisiae

The mechanism of action of valproate (VPA), a widely prescribed short chain fatty acid with anticonvulsant and anticancer properties, remains poorly understood. Here, the yeast Saccharomyces cerevisiae was used as model to investigate the biological consequences of VPA exposure. We found that low pH...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Desfossés-Baron, Kristelle, Hammond-Martel, Ian, Simoneau, Antoine, Sellam, Adnane, Roberts, Stephen, Wurtele, Hugo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080547/
https://ncbi.nlm.nih.gov/pubmed/27782169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36013
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