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An interplay between multiple sirtuins promotes completion of DNA replication in cells with short telomeres
The evolutionarily-conserved sirtuin family of histone deacetylases regulates a multitude of DNA-associated processes. A recent genome-wide screen conducted in the yeast Saccharomyces cerevisiae identified Yku70/80, which regulate nonhomologous end-joining (NHEJ) and telomere structure, as being ess...
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| Publicat a: | PLoS Genet |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5919697/ https://ncbi.nlm.nih.gov/pubmed/29659581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007356 |
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