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Chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore

High-fidelity transmission of the genome through cell division requires that all sister kinetochores bind to dynamic microtubules (MTs) from opposite spindle poles. The application of opposing forces to this bioriented configuration produces tension that stabilizes kinetochore–microtubule (kt–MT) at...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Ye, Anna A., Cane, Stuart, Maresca, Thomas J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080440/
https://ncbi.nlm.nih.gov/pubmed/27762268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13221
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