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Chromosome biorientation produces hundreds of piconewtons at a metazoan kinetochore

High-fidelity transmission of the genome through cell division requires that all sister kinetochores bind to dynamic microtubules (MTs) from opposite spindle poles. The application of opposing forces to this bioriented configuration produces tension that stabilizes kinetochore–microtubule (kt–MT) at...

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Publicat a:Nat Commun
Autors principals: Ye, Anna A., Cane, Stuart, Maresca, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080440/
https://ncbi.nlm.nih.gov/pubmed/27762268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13221
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