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Impact of AmpC Derepression on Fitness and Virulence: the Mechanism or the Pathway?

Understanding the interplay between antibiotic resistance and bacterial fitness and virulence is essential to guide individual treatments and improve global antibiotic policies. A paradigmatic example of a resistance mechanism is the intrinsic inducible chromosomal β-lactamase AmpC from multiple Gra...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Pérez-Gallego, Marcelo, Torrens, Gabriel, Castillo-Vera, Jane, Moya, Bartolomé, Zamorano, Laura, Cabot, Gabriel, Hultenby, Kjell, Albertí, Sebastián, Mellroth, Peter, Henriques-Normark, Birgitta, Normark, Staffan, Oliver, Antonio, Juan, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080387/
https://ncbi.nlm.nih.gov/pubmed/27795406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01783-16
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