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Impact of Derepressed AmpC β-Lactamase ACT-9 on the Clinical Efficacy of Ertapenem

An in vivo development of Pantoea agglomerans mutants (isolates PA2 to PA4) with reduced ertapenem susceptibility from that of isolate PA1 was associated with an inadequate clinical response to ertapenem therapy. All four isolates harbored the bla(ACT-9) AmpC β-lactamase gene. However, a loss-of-fun...

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Autori principali: Lee, Yi-Tzu, Chen, Te-Li, Siu, Leung-Kei, Chen, Chien-Pei, Fung, Chang-Phone
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165326/
https://ncbi.nlm.nih.gov/pubmed/21690276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00271-11
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