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Impact of Derepressed AmpC β-Lactamase ACT-9 on the Clinical Efficacy of Ertapenem

An in vivo development of Pantoea agglomerans mutants (isolates PA2 to PA4) with reduced ertapenem susceptibility from that of isolate PA1 was associated with an inadequate clinical response to ertapenem therapy. All four isolates harbored the bla(ACT-9) AmpC β-lactamase gene. However, a loss-of-fun...

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Bibliografische gegevens
Hoofdauteurs: Lee, Yi-Tzu, Chen, Te-Li, Siu, Leung-Kei, Chen, Chien-Pei, Fung, Chang-Phone
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165326/
https://ncbi.nlm.nih.gov/pubmed/21690276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00271-11
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