Pseudomonas aeruginosa Ceftolozane-Tazobactam Resistance Development Requires Multiple Mutations Leading to Overexpression and Structural Modification of AmpC

We compared the dynamics and mechanisms of resistance development to ceftazidime, meropenem, ciprofloxacin, and ceftolozane-tazobactam in wild-type (PAO1) and mutator (PAOMS, ΔmutS) P. aeruginosa. The strains were incubated for 24 h with 0.5 to 64× MICs of each antibiotic in triplicate experiments....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cabot, Gabriel, Bruchmann, Sebastian, Mulet, Xavier, Zamorano, Laura, Moyà, Bartolomé, Juan, Carlos, Haussler, Susanne, Oliver, Antonio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Mechanisms of Resistance
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068469/
https://ncbi.nlm.nih.gov/pubmed/24637685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02462-13
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak