Dual-Reporter Mycobacteriophages (Φ(2)DRMs) Reveal Preexisting Mycobacterium tuberculosis Persistent Cells in Human Sputum

Persisters are the minor subpopulation of bacterial cells that lack alleles conferring resistance to a specific bactericidal antibiotic but can survive otherwise lethal concentrations of that antibiotic. In infections with Mycobacterium tuberculosis, such persisters underlie the need for long-term a...

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Bibliographic Details
Published in:mBio
Main Authors: Jain, Paras, Weinrick, Brian C., Kalivoda, Eric J., Yang, Hui, Munsamy, Vanisha, Vilcheze, Catherine, Weisbrod, Torin R., Larsen, Michelle H., O’Donnell, Max R., Pym, Alexander, Jacobs, William R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080378/
https://ncbi.nlm.nih.gov/pubmed/27795387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01023-16
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